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Oxidative stress in the rats' cardiac tissue was assessed by measuring biomarkers, including superoxide dismutase (SOD), catalase (CAT), and malondialdehyde (MDA), using the ELISA method

Research cycles typically run for 4 to 8 weeks, often followed by a break of 2 to 4 weeks before potentially resuming

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Some notice changes within a week, while others see gradual improvement over several weeks

doi: 10.1186/S12947-019-0177-8 34 MarranoNBiondiGCignarelliAPerriniSLaviolaLGiorginoFet al

MMP-1, MMP-2, MMP-9 GHK-Cu has been shown to suppress matrix metalloproteinases (MMPs) that degrade collagen and elastin, preserving dermal structural integrity